tryptamine ,cas 61-54-1

Synonyms
2-(1H-Indol-3-yl)ethylamine
Tryptamine
1H-Indole-3-ethanamine
2-indol-3-yl-ethylamine
Indole-ethylamine
L-TRYPTAMINE
EINECS 200-510-5
2-Indol-3-yl-aethylamin
Tryptamin
3-Indoleethanamine
2-(1H-Indol-3-yl)ethanamine
MFCD00005661
TRYPTAMINE(P)
125513
T56 BMJ D2Z
[2-(1H-indol-3-yl)-ethyl]amine
TRIPTAMINE
(1H-indol-3-yl)ethanamine
2-indol-3-ylethylamine
Common Name tryptamine
CAS Number 61-54-1 Molecular Weight 160.216
Density 1.2¯0.1 g/cm3 Boiling Point 378.8¯0.0 ®C at 760 mmHg
Molecular Formula C10H12N2 Melting Point 113-116 ®C(lit.)
Flash Point 187.7¯8.1 ®C
tryptamine Biological Activity
Description Tryptamine is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter.
Related Catalog
Natural Products >> Alkaloid
Research Areas >> Others
Target
Human Endogenous Metabolite

References
[1]. Jones RS, et al. Tryptamine: a neuromodulator or neurotransmitter in mammalian brain? Prog Neurobiol. 1982;19(1-2):117-39.
CHEMICAL IDENTIFICATION
RTECS NUMBER :
NL4020000
CHEMICAL NAME :
Indole, 3-(2-aminoethyl)-
CAS REGISTRY NUMBER :
61-54-1
BEILSTEIN REFERENCE NO. :
0125513
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H12-N2
MOLECULAR WEIGHT :
160.24
WISWESSER LINE NOTATION :
T56 BMJ D2Z
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
223 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 66,1692,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,453,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 22,313,1970