polygonum cuspidatum extract

1ÿ¢Antipyretic and Analgesic Activity
2ÿ¢Anti-cancer and Anti-mutagen Activity
Resveratrol exhibits cancer chemo-preventive activity by acting as an antioxidant, an antimutagen, and an anti-inflammatory agent. It also induces human promyelocytic leukemia cell differentiation (anti-progression activity) and inhibits the development of preneoplastic lesions. Resveratrol can also inhibit protein-tyrosine kinase, which catalyzes the phosphorylation of tyrosine. This kinase is involved in signal transduction in the cytoplasm of a cell involved in the regulation of mitogenesis. The inhibition of protein-tyrosine kinase by resveratrol is possibly antimutagenic by detering the kinases function.
3ÿ¢Prevention of Heart and Liver Damage
Resveratrol inhibits the deposition of triglycerides and cholesterol in the liver of mice. It also reduces the elevation of aspartate transaminase and alanine transaminase. Analysis of these two enzymes in blood serum gives good diagnostic information for heart and liver damage.
4ÿ¢Antithrombotic Activity
Resveratrol inhibits lipoxygenase production, which are enzymes found in leukocytes, the heart, brain, lung, and spleen. Thus resveratrol prevents the formation of blood clots within blood vessels. It also inhibits platelet aggregation after treatment with clonidine, an antihypertensive drug.
5ÿ¢Immune System Improvement in Wound Healing
Polygonum Cuspidatum P.E.