letrozole white powder

Product name: letrozole white powder
Trade name:Femara
CAS NO: 112809-51-5
letrozole Content: 99%
Molecular Formula: C17H11N5 letrozole
Quality standard: USP29
Apperance: off-white crystal
Packing: as your require
Storage: shading, confined preservation.
Letrozole is an oral non-steroidal inhibitor for the treatment of hormonally-responsive breast cancer after surgery
letrozole prevents the aromatase from producing estrogens by competitive,reversible binding to the heme of its cytochrome p450 unit,the action is specific,and letrozol does not reduce production of mineralo-or corticosteroids
in cotrast ,tamoxifen interferes with estrogen receptor,tamoxifen is also used to treat hormonally-responsive breast cancer.however.letrozol is effective only in post-menopausal women,in whom estrogen is produced predominantly in the main source od estrogen is from the ovaries not the peripheral tissues,and letrozol is ineffective
Letrozole is approved by the FDA for the treatmeny of local or metastatic breast cancer that is hormone receptor postive or has an unknown receptor status in postmenopausal women
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