Testosterone Undecanoate

Testosterone Undecanoate
Email: *
Quick details:

Product name: Testosterone Undecanoate
Alias: Andriol
CAS No: 5949-44-0
Einecs No: 227-712-6
MF: C30H48O3
MW: 456.7
Melting point 59-61®C
storage temp. Controlled Substance, -20?C Freezer
Product catagory: Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Steroids;
Steroid and Hormone;Finished Steroid and Hormone;API;testosterone
Usage: A metabolite of Testosterone. CONTROLLED SUBSTANC ; A metabolite of Testosterone (T155000). It is a promising androgen for male hormonal contraception.


OBJECTIVE:

We determined the effect of 3 months of daily, 40 mg oral testosterone undecanoate on growth, body composition, hand grip and quadriceps muscle strength, and total free-living daily energy expenditure in boys with constitutionally delayed puberty.

MEASUREMENTS:

Body composition measurements were made by skinfold thickness, bioelectrical impedance and stable isotope dilution (H2(18)O) methods. Energy expenditure was assessed by the doubly-labelled water (2H2(18)O) technique.

RESULTS:

Height velocity increased from 5.4 (0.8) to 8.1 (0.6) cm/year (P < 0.05) in the 3 months after active therapy. Fat-free mass increased more with therapy (2.7 (0.3) kg) over the 6-month study period than with placebo (1.7 (0.4) kg, P < 0.5). Height velocity increases correlated with daily increases in fat-free mass (r = 0.68, P = 0.005) in the study group as a whole. Energy expenditure and muscle strength increased similarly in both groups. Predicted adult height decreased in the group which was treated with testosterone undecanoate.