Tesofensine Powder

What is Tesofensine powder?
Tesofensine (TE) inhibits the presynaptic reuptake of the neurotransmitter’s noradrenaline,dopamine and serotonin.Other types of selective serotonin reuptake inhibitors are used to treat depression and eating disorders,but they have generally failed to produce sustained weight loss.Sibutramine,in addition to its effect on serotonin,also inhibits the reuptake of other monoamines and has been shown to enhance postprandial satiety,reduce total calorie intake and to diminish the decline in energy expenditure usually associated with a diet-induced negative energy balance.

Tesofensine (TE) was originally studied for its effect on Parkinson’s and Alzheimer’s.Unfortunately,its exploration for these indications were limited because the patients were starting to lose too much weight.Since then,tesofensine has been studied as a way to treat obesity via its ability to reduce appetite.TE indirectly stimulates the cholinergic system and showed to be more successful than average weight loss remedies .

Tesofensine increases near transmission of a reuptake inhibitor 3 monoaminergic neurotransmitters in the brain.These neurotransmitters are serotonin,norepinephrine,and dopamine which help regulate energy balance and are linked to obesity and depression.On average,according to research,its 6-month weight loss results from research trials resulted in a weight loss of around 25 pounds.
Key Benefits of Tesofensine
Tesofensine for Weight Loss
Since discovering its ability to suppress appetite and aid in fat oxidation,researchers have diligently investigated the tesofensine obesity treatment.

The clinical Phase 2B trial results[ii] indicate that tesofensine produces approximately 28.2 lbs of weight loss on a 1 mg dose,24.9 lbs on a 0.3 mg dose,and 14.7 lbs on a 0.25 mg dose.All patients were instructed to follow a 300-calorie deficit diet and to engage in 30-60 minutes of physical exercise per day.

Research shows that tesofensine produced the best results when paired with caloric restrictions and exercise.

Other tesofensine results noted by patients include improved levels of insulin sensitivity,appetite reduction,an increase in energy after 14 days,and an increase in fat oxidation – and ultimately a reduction in fat tissue.

In the phase 3 study,a 24-week double-blinded trial,patients were given 0.25mg and 0.50mg of oral tesofensine.Results found a decrease in body weight,reduction in BMI,decreased body fat,decreased insulin,and improvements in hip and waist circumference.There was even evidence to suggest that tesofensine pills or capsules could better regulate glucose metabolism and even potentially reverse early type 2 diabetes.

From what’s been discovered at present,this peptide looks to be a ground-breaking formula when it comes to the treatment of obesity and diabetes.

Tesofensine for Depression
According to research,tesofensine may be helpful for depression.Research demonstrates that stress can decrease BDNF levels in the brain – that is responsible for stimulating neuron growth and easing symptoms in those with depression and cognitive decline.When this exposure to stress becomes chronic and prolonged,atrophy of the hippocampus can occur.This change in the structure of the hippocampus has been linked to depression.

Studies show that tesofensine can improve BDNF levels and ultimately promote neurogenesis in the brain,offering anti-depressant properties.While it’s not been the primary focus of research,it’s clear that tesofensine capsules can be effective at easing mental health issues like depression.

Tesofensine for Alzheimer’s
While researchers may have abandoned the use of tesofensine in the treatment of Alzheimer’s and Parkinson’s,there’s still enough evidence to show the compound boasts beneficial effects on memory and cognition.Despite the dopamine-boosting effects being too small to have a great impact on these neurological diseases,some scientists are still interested in harnessing the peptide’s cognitive-enhancing abilities.

As previously mentioned,tesofensine peptide can increase BDNF levels.This,in turn,can help boost cell survival and reproduction.Experts are convinced this compound may be helpful for a range of conditions,including depression,obsessive-compulsive disorder,and Alzheimer’s.

Tesofensine for Pain Management
While research is limited on these effects,there is evidence to suggest that this anti-depressant may be able to help when it comes to managing pain.Thanks to dopamine-boosting agents,tesofensine may aid in quelling pain.Of course,the current research focus is on its ability to boost weight loss.That said,scientists do believe they’ll find more benefits of tesofensine the more they investigate the compound..
When buying Tesofensine Powder, it is important to ensure that you are sourcing from a reputable and reliable supplier to ensure the quality and integrity of the product. AASraw is a trusted supplier. For wholesale orders, you will get very competitive prices.

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