Tamoxifen Citrate (Nolvadex)

By reducing membrane negotiability and enhancing rigidity of inter-cell binding site, Tamoxifen citrate can reduce concentration and activity of cancer metastasis promoter and various activating enzymes, so as to inhibit or hinder growth and metastasis of cancer cell. In addition, it can promote cells surrounding tumor focus to secrete a negative growth factor-transforming growth factor TGF-G, inhibiting multiply indefinitely of cancer cells; inhibiting oxidative damage of DNA bases which is caused by hydrogen peroxide generated from human neutrophils. So except for breast cancer, it is good for treatment and prevention of other malignant neoplasms, and is used for treatment of brain tumors, liver cancer, prostate cancer, etc. In addition, Tamoxifen citrate can reduce release effect of membrane P170 glycoprotein through reducing membrane negotiability, improving intracellular effective concentration of cytotoxic drug and reducing drug resistance.

4. Heart protection.

Use/Dosing

In terms of dosing for combating gynocomastia that has begun to form, there is very little research. The limited research that does exist does point to the fact that doses of 20-40mgs per day are effective in treating the existing condition . However, anecdotally users have reported sometimes using doses of 60-80mgs per day. These doses may have more to do with users' impatience rather than the need for higher doses, as no research indicates that such doses are needed. It should be noted as well however that tamoxifen citrate may have no effect on existing gynocomastia in some individuals. Many users have indicated that the compound will only help alleviate symptoms if the gynocomstia has not been apparent for a long period of time. Of course, this is all subjective and the effectiveness of the drug can only be determined on a trial and error basis.

For use during post-cycle therapy users have anecdotally indicated that doses ranging between 20 and 40mgs per day are average. These doses have been shown to significantly raise levels of testosterone, luteinizing hormone and follicle stimulating hormone. Most users have reported when using tamoxifen citrate for their post-cycle therapy they will administer the drug for a minimum of three weeks. A maximum length has not necessarily been established due to the few side effects associated with the compound. In this case, this compound can be run for as long as wanted with little to no concern being needed to be paid to potential side effects.


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