Pregabalin

CAS No.148553-50-8
Chemical Name:Pregabalin
SynonymsLyrica;Pregablin;Pregabali;PREGABAIN;PREGABALIN;Neugaba 75;Pregabilin;Prebagalin;Maxgalin 75;TOS-BB-0910
CBNumber:CB2251105
Molecular Formula:C8H17NO2
Formula Weight:159.23
MOL File:148553-50-8.mol
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Properties Safety Price10 Uses Suppliers 592
Pregabalin
Pregabalin Properties
Melting point:194-196®C

Description
Pregabalin is a second- generation antiepileptic drug (AED) known with the proprietary brand name of Lyrica¬ (Pfizer, Tadworth) in the UK and USA (Pfizer, New York, NY).
Generic formulation
MHRA/ CHM advice to minimize risk when switching patients with epilepsy between different manufacturers’ products (including generic products):
It is usually unnecessary to ensure that patients are maintained on a specific manufacturer’s product unless there are specific concerns, such as patient anxiety and risk of confusion/ dosing error.
Indications
Epilepsy
Adjunctive therapy of focal seizures with and without secondary generalization.


alpha D23 +10.52® (c = 1.06 in water)
Boiling point:274.0¯23.0 ®C(Predicted)
Density 0.997¯0.06 g/cm3(Predicted)
Flash point:9℃
storage temp. Store at RT
solubility deionized water: ≥10mg/mL
form white powder
pka4.23¯0.10(Predicted)
InChIKeyAYXYPKUFHZROOJ-ZETCQYMHSA-N
CAS DataBase Reference148553-50-8(CAS DataBase Reference)
EWG's Food Scores1
FDA UNII55JG375S6M
NCI Dictionary of Cancer TermsLyrica; pregabalin
SAFETY
Risk and Safety Statements
Symbol(GHS)
GHS02,GHS06,GHS08,GHS05
Signal word Danger
Hazard statements H318-H361-H225-H301+H311+H331-H370
Precautionary statements P210-P260-P280-P301+P310-P311-P305+P351+P338+P310-P305+P351+P338
Hazard Codes Xn,T,F
Risk Statements 63-48/22-39/23/24/25-23/24/25-11
Safety Statements 22-36/37-45-16-7
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 3