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Pirfenidone
Price: | US$ 10 / Unit |
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Minimum Order: | 10 |
Payment Terms: | Western Union, Money Gram, Bank Transfer, Bitcoin, |
Port of Export: | SHENZHEN |
Product Details
Model No.: | 53179-13-8 | Brand Name: | RAWSGEAR |
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Certification: | ISO9001 |
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Specification: |
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity. |
Packaging & Delivery
Packaging: | Foil bag and Disguised bag |
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Delivery/Lead Time: | 3-5 work days |
Production Capacity: | 1000kg/month |
Product Description
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity. Web: *
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Skype: +8615711952876
Whatsapp +8615711952876
SUPPLIER PROFILE
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Company: | Wuhan Shuiyi Technology Co., Ltd. | ||
City/State | wuhan, Hubei | Country: | China |
Business Type: | Export - Manufacturer / Trading Company | Established: | 2017 |
Member Since: | 2019 | Contact Person | Julia sum |
SUPPLIER PROFILE
City/State/Country -
wuhan, Hubei
China
Business Type -
Export - Manufacturer / Trading Company
Established -
2017
Member Since -
2019
Contact Person -
Julia sum