Myricetin

Botanical Name: Ampelopsis grossedentata W.T.Wang.

Synonyms: 3,3',4',5,5',7-Hexahydroxyflavone; Cannabiscetin.

Chemical Name: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one

Botany: Myricetin is flavonol, found in many grapes, berries, fruits, vegetables, herbs, as well as other plants. Walnuts are a rich dietary source. Kingherbs is used from the Ampelopsis grossedentata, it is called Teng cha in China. Myricetin is consisting of 3-hydroxyflavone backbone and 6 hydroxyl groups. Pure Myricetin mainly occurs in nature in the form of glycosides.

Function:

1.Clear the free radical;

2.Anti-oxidation;

3.Modify LDL cholesterol, improve heart health by preventing LDL oxidation and reducing the uptake of oxidized LDL by macrophages;

4.Diminish inflammation;

5.Anti-fungi/bacterium;

6.Preventing the forming of the thrombus,

7.Anti-tumour & cancer, antimutagenic, especially good for prostate cancer, leukemia, nasopharyngeal darcinoma/NPC, pancreatic cancer;

8.Protect liver;

9.Improve bone-health;

10.Myricetin inhibits the uptake of methylglucose by adipocytes, reduces oxidative injury in diabetes related bone diseases and reduces glucose plasma level in diabetic rats;

11.Myricetin inhibits ROS production caused by glutamate and reduces glutamate-induced activation of caspase-3. Myricetin restored dopamine level in laboratory animals with induced Parkinsonism. Myricetin may also inhibit beta-amyloid fibril formation in Alzheimer patients.

Active Ingredient: Ampelopsis grossedentata contains rich flavones, amino acids, vitamins; proteins and essential trace element.
The flavones are mainly dihydromyricetin, myricetin, quercetin, quercetin-5-O-β–D-glucoside, taxifolin, apiin.

Myricetin:

CAS#: 529-44-2

EINECS: 208-463-2

Molecular Formula: C15H10O8

Molecular Weight: 318.24

Part of the plant used: Leaf.

Appearance: Fine yellow-beige crystalline powder.

Extract solvents: Ethanol & water.

Solubility: easy soluble in hot water, hot ethanol and acetone, soluble in ethanol, methanol, slightly soluble acetic ether, insoluble in chloroform, petroleum ether.

Stability: stable in heat, but when heated to 100°C above, it will be oxidized irreversibly. It is stable in acidity and neutral.

Test Method: HPLC.

Specification: Myricetin 50%, 80%, 98% (HPLC).