MGF, 2mg/vial

MGF, 2mg/vial

Sequence: Tyr - Gln - Pro - Pro - Ser - Thr - Asn - Lys - Asn - Thr - Lys - Ser - Gln - D - Arg - D - Arg - Lys - Gly - Ser - Thr - Phe - Glu - Glu - His - Lys - NH2
M.W: 2848.13
Solubility: Insoluble in water. Dissolve peptide in 50-100 µl of 60% Acetonitrile in water or DMSO, then dilute with any desired buffer.
Storage Condition: Store peptide in DRY form at 0-5°C.
Appearance: White powder
Content: The contents of this vial have been accurately determined to contain 100µg of NET peptide.
HPLC Analysis Purity ≥95%
Action:When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the up regulation of new protein synthesis. After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an inject able peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth.