Local Anesthetic Amethocaine CAS 94-24-6 Tetracaine Pain Reliever 99% Purity jay at ycgmp dot com

Description

Tetracaine is a local anesthetic (numbing medicine). It works by blocking nerve signals in your body. Tetracaine topical may also be used for purposes not listed in this medication guide. Tetracaine topical (for the skin) is used to numb different parts of the body before a medical test or procedure.

Application

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

Usage

Used for mucosal epidermal anesthesia, nerve tissue anesthesia, epidural anesthesia and Subarachnoid space anesthesia.
In the manufacture of pharmaceutical preparation for external use, to relieve the pain of drugs or medication lesions pain

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