Inquriy About High Purity Cas401900-40-1

1 Due to seasonal and market reasons, the price of the product will inevitably fluctuate. For the actual price, please send an inquiry

2 If you are not very clear about the product quality, use, content, etc., please send an inquiry

3 Delivery within 3 days of payment, delivery can be fast and convenient with eub, DHL, UPS, FEDEX, etc. If you have special requirements, please tell me when paying

4 The company adheres to the business philosophy of "customer first" and adheres to the principle of "customer first" to provide our customers with high-quality services.



SARM S4 Properties

melting point: 70-74℃
boiling point: 698.7¯55.0 ®C(Predicted)
density:
1.47

Storage conditions: Refrigerator
Acidity coefficient (pKa): 12.13¯0.29(Predicted)
form: neat
BRN: 9666695
InChIKey:

YVXVTLGIDOACBJ-SFHVURJKSA-N
molecular weight: 441.36


CBNumber:CB82473534

molecular formula:C19H18F3N3O6





SARM S4 properties, uses and production process

biological activity

Andarine is a selective non-steroidal androgen receptor (AR) (androgen receptor) agonist with Ki of 4 nM, tissue-selective for anabolic organs. Phase 3.

In vitro studies

In vitro, Andarine binds to the androgen receptor with high affinity with a Ki of 4 nM. Furthermore, 10 nM Andarine stimulated androgen receptor-regulated transcription by 93%.

In vivo studies

In vivo, Andarine has potent anabolic activity and stimulates prostate, seminal vesicle, and levator ani muscle growth with ED50 of 0.43 mg/day, 0.55 mg/day, and 0.14 mg/day, respectively, in a dose-dependent manner . In addition, Andarine acts on FSH, has no effect on some physiological changes caused by castration, and partially inhibits LH production at doses of 0.5 mg per day or higher. Intravenous administration of Andarine at 0.1, 1, 3, and 10 mg/kg in dogs reduced total body clearance (CL) from 7.4 mL/min/kg to 3.1 mL/min/kg, volume of distribution at steady state (Vss) It was 1.39 L/kg and the half-life was 229 minutes. In addition, andarine was administered at 10 mg/kg, 1 mg/kg and 0.1 mg/kg with oral bioavailability of 38%, 62% and 91%, respectively. Andarine has tissue-selective pharmacological activity, and treatment of intact rats at a concentration of 0.5 mg/day significantly reduces prostate weight to 79.4%.

feature

Andarine is a nonsteroidal androgen receptor (AR) selective stimulant.

biological activity

Andarine (GTx-007, S-4) is a selective non-steroidal androgen receptor (AR) (androgen receptor) agonist with Ki of 4 nM, tissue selective for anabolic organs. Phase 3.

target

Target Value

Androgen Receptor 4 nM(Ki)



In vitro studies

In vitro, Andarine binds to the androgen receptor with high affinity with a Ki of 4 nM. Furthermore, 10 nM Andarine stimulated androgen receptor-regulated transcription by 93%.



In vivo studies

In vivo, Andarine has potent anabolic activity and stimulates prostate, seminal vesicle, and levator ani muscle growth with ED50 of 0.43 mg/day, 0.55 mg/day, and 0.14 mg/day, respectively, in a dose-dependent manner . In addition, Andarine acts on FSH, has no effect on some physiological changes caused by castration, and partially inhibits LH production at doses of 0.5 mg per day or higher. Intravenous administration of Andarine at 0.1, 1, 3, and 10 mg/kg in dogs reduced total body clearance (CL) from 7.4 mL/min/kg to 3.1 mL/min/kg, volume of distribution at steady state (Vss) It was 1.39 L/kg and the half-life was 229 minutes. In addition, andarine was administered at 10 mg/kg, 1 mg/kg and 0.1 mg/kg with oral bioavailability of 38%, 62% and 91%, respectively. Andarine has tissue-selective pharmacological activity, and treatment of intact rats at a concentration of 0.5 mg/day significantly reduces prostate weight to 79.4%.








FAQ

Q1: Can I get a sample?
A:Free samples is available, while the shipping cost should undertake by your side.

Q2: What is your MOQ?
A:Our MOQ is 10g, 100g and 1kg for your evaluation quality of our goods on the condition that
sample charge is 100% paid.

Q3: Is there any discount?
A:Yes, for larger quantity, we always support with better price.

Q4: What payment terms do you accept ?
A:We'd like to accept T/T, L/C, Paypal, or Western Union.

Q5: How long will it take to get the good?
A:Depending on your location, For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS. For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q6: How do you treat quality complaint?
A:First of all, our quality control will ensure the product quality in advance. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.