Human Neurons

Human Neurons (HN) mainly reside in central nervous system, but also distribute in multiple other parts of the brain such as peripheral ganglia, retina and cochlea. Neurons are highly specialized for the processing and transmission of cellular signals. Transmitting information is the exceptional character that distinguishes neurons from other cells. Neuron stops reproduction shortly after birth and is unable to replace the old one. Consequently, some diseases like neurodegenerative disease (e.g. Parkinson's disease, Alzheimer's disease and Huntington's disease) that damage nerve cells are hard to cure. Another obstacle of research on human nervous system research is the lack of neuronal cells due to the difficulty of isolating neurons from living patients. Primary neurons can be easily cultured and differentiated into neurons. Thus, primary neurons culture has become one of the most elementary methodologies for modern neurobiology.

Applications
Human Neurons are a proven model system for studying brain functions and diseases. The most common applications are as follows:
-Neurodegenerative disease modeling
-Drug screening test by a microscopy-based high-throughput method
-Development of 3D engineered culture

Human 3D neuronal cell culture is instrumental in developing new technologies for drug creating and testing to reduce the risks.