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Human NMBR/Galpha15 Stable Cell Line-Chem-1
Price: | US$ 1 / Gram |
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Payment Terms: | Yes |
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Product Details
Model No.: | Brand Name: | Creative Biogene |
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Human NMBR/Galpha15 Stable Cell Line-Chem-1 |
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Product Description
Bombesin, a bioactive peptide first identified in amphibian skin, is related to two mammalian peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB). A family of 3 GPCRs, including NMB-R (BB1), GRP-R (BB2) and BRS-3 (BB3), mediate the biological effects of the peptides. The receptors differ in their affinities for the peptides; BB2 binds to GRP with 50-300-fold greater affinity than to NMB, whereas BB1 binds to NMB with 10-800-fold greater affinity than to GRP. Binding of ligand to BB1 activates Gq to increase intracellular calcium concentrations. The CNS is a major site of NMB and BB1 expression, and BB1 appears to be involved in thermoregulation. creative-biogene.com/Human-NMBR-Galpha15-Stable-Cell-Line-Chem-1-195516-11.html
SUPPLIER PROFILE
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Company: | Creative Biogene | ||
City/State | Shirley, NY | Country: | United States |
Business Type: | Export/Import - Trading Company | Established: | 2005 |
Member Since: | 2017 | Contact Person | Wendy Wilson |
SUPPLIER PROFILE
City/State/Country -
Shirley, NY
United States
Business Type -
Export/Import - Trading Company
Established -
2005
Member Since -
2017
Contact Person -
Wendy Wilson