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Human CNR1/Galpha15 Stable Cell Line-Chem-1
Price: | US$ 1 / Gram |
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Payment Terms: | Yes |
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Product Details
Model No.: | Brand Name: | Creative Biogene |
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Human CNR1/Galpha15 Stable Cell Line-Chem-1 |
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Product Description
CB1 is a GPCR that is expressed primarily in brain and nervous tissue, and mediates numerous CNS responses such as analgesia, appetite, cognition, memory and locomotor activity. A number of cannabinoid ligands bind to CB1 and activate Gi/o-mediated downstream responses, including inhibition of cAMP production and activation of ion channels and MAP kinases. Such ligands include exogenous agonists such as Delta9-THC, the main psychoactive component of the plant Cannabis sativa, and endogenous agonists such as anandamide that belong to eicosanoid family. A number of synthetic agonists such as CP55940 and R-(+)-WIN55212, and antagonists, such as SR141716A, for CB1 have been developed. CB1 agonists have clinical utility in analgesia and antiemetic properties, whereas CB1 antagonists show promise for treatment of appetite in obesity disorders. creative-biogene.com/Human-CNR1-Galpha15-Stable-Cell-Line-Chem-1-195522-11.html
SUPPLIER PROFILE
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Company: | Creative Biogene | ||
City/State | Shirley, NY | Country: | United States |
Business Type: | Export/Import - Trading Company | Established: | 2005 |
Member Since: | 2017 | Contact Person | Wendy Wilson |
SUPPLIER PROFILE
City/State/Country -
Shirley, NY
United States
Business Type -
Export/Import - Trading Company
Established -
2005
Member Since -
2017
Contact Person -
Wendy Wilson