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Human CCR3/Galpha15 Stable Cell Line-Chem-1
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  • Human CCR3 Galpha15 Stable Cell Line
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Human CCR3/Galpha15 Stable Cell Line-Chem-1

Price: US$ 1 / Gram
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Product Details
Model No.: Brand Name: Creative Biogene
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Specification: Human CCR3/Galpha15 Stable Cell Line-Chem-1
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Product Description
Eosinophils are major effector cells implicated in a number of chronic inflammatory diseases in humans, particularly bronchial asthma and allergic rhinitis. The chemokine receptor 3 (CCR3), a GPCR activated by chemokines eotaxin 1/2, MCP-3, MCP-4, and RANTES, mediates selective recruitment of eosinophils into tissue and thus has recently become an attractive biological target for therapeutic intervention. It is widely expressed on cells involved in allergic inflammation, such as basophils, mast cells, airway epithelial cells, and potentially TH2 T-lymphocytes. Allergen-induced eosinophil infiltration into airways is reduced or eliminated in CCR3 and eotaxin 1/2 knockout mice mice and in mice treated with antibodies directed against CCR3. CCR3 antagonists are currently being developed for the treatment of asthma and other allergic disorders.
creative-biogene.com/Human-CCR3-Galpha15-Stable-Cell-Line-Chem-1-195528-11.html
Human CCR3/Galpha15 Stable Cell Line-Chem-1
SUPPLIER PROFILE
Company: Creative Biogene
City/State Shirley, NY Country: United States  
Business Type: Export/Import - Trading Company Established: 2005
Member Since: 2017 Contact Person Wendy Wilson
SUPPLIER PROFILE
City/State/Country -
Shirley, NY
United States  
Business Type -
Export/Import - Trading Company
Established -
2005
Member Since -
2017
Contact Person -
Wendy Wilson