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Human CALCRL/Galpha15 Stable Cell Line-Chem-1
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  • Human CALCRL Galpha15 Stable Cell Line
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Human CALCRL/Galpha15 Stable Cell Line-Chem-1

Price: US$ 1 / Gram
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Product Details
Model No.: Brand Name: Creative Biogene
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Specification: Human CALCRL/Galpha15 Stable Cell Line-Chem-1
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Product Description
The calcitonin family of peptides, which includes calcitonin, two calcitonin-related gene peptides (CGRPs), adrenomedullin, and amylin, share a disulfide-bonded loop, an amphipathic a-helix, and an amidated C-terminus. The peptides influence a variety of physiological effects, including vascular tone, food intake and bone metabolism. The biological effects of the peptides are mediated by two class B GPCRs, CT receptor (calcitonin receptor) and CL receptor (calcitonin receptor-like receptor). The pharmacology of the CT and CL receptors is strongly influenced by their association with a family of three receptor activity modifying proteins (RAMPs), which are 14-17 kD single pass transmembrane proteins. CGRP (calcitonin gene-related peptide) induces vasodilation, and its activity is primarily mediated by CGRP1, composed of CL in complex with RAMP1. As a consequence of its role as a vasodilator, CGRP acting via CGRP1 appears to play an important role in hypertension.
creative-biogene.com/Human-CALCRL-Galpha15-Stable-Cell-Line-Chem-1-195520-11.html
Human CALCRL/Galpha15 Stable Cell Line-Chem-1
SUPPLIER PROFILE
Company: Creative Biogene
City/State Shirley, NY Country: United States  
Business Type: Export/Import - Trading Company Established: 2005
Member Since: 2017 Contact Person Wendy Wilson
SUPPLIER PROFILE
City/State/Country -
Shirley, NY
United States  
Business Type -
Export/Import - Trading Company
Established -
2005
Member Since -
2017
Contact Person -
Wendy Wilson