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High purity Montelukast sodium powder cas no. 151767-02-1 MF.C35H35ClNNaO3S
Price: | US$ 1 |
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Minimum Order: | 0.1kG |
Payment Terms: | TT/LC/WEST UNION/ALIPAY |
Port of Export: | shenzheng |
Product Details
Model No.: | CAS 151767-02-1 | Brand Name: | gx shunjie |
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Certification: | GMP/SGS/CE/FDA/ISO/TUV |
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Specification: |
Montelukast sodium CAS No.:151767-02-1 EINECS(EC#): 604-813-7 Molecular Weight:608.169 Molecular Formula:C35H35ClNNaO3S abby(at)gxsjjck dot cim erin(at)gxsjjck dot cim |
Packaging & Delivery
Packaging: | custom |
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Delivery/Lead Time: | 3days |
Production Capacity: | 500kg/week |
Product Description
High purity Montelukast sodium powder cas no. 151767-02-1 Montelukast Sodium is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affecton
the CysLT2 receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 -
sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a
biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and
immune system function.Because of its method of operation, it is not useful for the treatment of acute asthma attacks. Again
because of its very specific mechanism of action, it does not interact with other asthma medications such as theophylline.Another
leukotriene receptor antagonist is zafirlukast (Accolate), taken twice daily. Zileuton (Zyflo), an asthma drug taken four times
per day, blocks leukotriene synthesis by inhibiting 5-lipoxygenase, an enzyme of the eicosanoid synthesis pathway.
Function:
Montelukastis a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of
seasonal allergies.Montelukast comes as a tablet, a chewable tablet, flash tablet and granules to take by mouth.Montelukast is
usually taken once a day with or without food.Montelukast is a CysLT1 antagonist; it blocks the action of leukotriene D4 (and
secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it.
This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.
Application:
Montelukast is used for a number of conditions including asthma, exercise induced bronchospasm, allergic rhinitis, primary
dysmenorrhoea and urticaria. It is mainly used as a complementary therapy in adults in addition to inhaled corticosteroids, if
they alone do not bring the desired effect. It is also used to prevent allergic reactions and asthma flare-ups during the
administration of intravenous immunoglobulin.
Specification
Raw Material Montelukast sodium powder 151767-02-1
SUPPLIER PROFILE
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Company: | Guangxi Shunjie Import and Export Co.,Ltd | ||
City/State | Nanning, Guangxi | Country: | China |
Business Type: | Export/Import - Trading Company | Established: | NA |
Member Since: | 2020 | Contact Person | Erin Bao |
SUPPLIER PROFILE
City/State/Country -
Nanning, Guangxi
China
Business Type -
Export/Import - Trading Company
Established -
NA
Member Since -
2020
Contact Person -
Erin Bao