Gynostemma Gypenosides

Gypenosides extracted from the Gynostemma pentaphyllum, is one major ingredient of GP.
Clinical application:
1, Promote healthy cardiovascular functions
A, Maintain normal cholesterol and triglyceride levels: Several scientific studies have shown that GP gypenosides are effective in assisting the body to reach normal serum lipid (cholesterol, triglycerides, etc.) levels. Using animal and human models, Investigators were able to demonstrate that the consumption of GP gypenosides helps the body system lower the high serum lipid levels and maintain those levels within the clinically normal ranges
B, Maintain a healthy blood pressure: GP gypenosides have been shown in many studies to increase blood circulation, decrease resistance in blood vessels, and induce vasorelaxation through promoting nitric oxide release. These combinations of effects act to normalize blood pressure.
C, Decrease vascular resistance and increase coronary blood flow: Several studies, summarized by Blumert and Liu in 1999, showed that animals given gypenosides had significantly reduced vascular resistance and platelet aggregation, and increased coronary blood flow. Xiong et al., in another animal study, successfully demonstrated the protective effect of GP on myocardial infarction.
D, Reduce vascular plaque: Atherosclerotic plaque is deposited in blood vessels as a result of the ù¬clumping?action of circulating platelets and high concentration of blood lipid, such as cholesterol. Studies shown that GP reduces platelet aggregation, helps to disperse any clumps that had begun to form, and lowers the blood lipid concentration.
2, Maintain normal blood glucose level. Functional studies of gypenosides on glucose metabolism using both animal and human models revealed that Gypenosides effectively reduced blood glucose level in animals and patients with diabetes mellitus.
3, Promote healthy liver functions. Lin et al evaluated the pharmacological effects of GP on carrageenan-induced paw edema and CCl4-induced hepatotoxicity in rats. . Gypenosides were found to possess significant anti-inflammatory activity against carrageenan induced edema. Most recently, Lin et al. published another paper concerning the antioxidant effect of GP and its hepatoprotective activity on acetaminophen-induced liver injury. The results suggested that GP acted as an antioxidant to protect liver cells and tissue from injury caused by chemicals such as acetaminophen. Hu et al. showed that gypenosides protected cultured rat liver cells from direct damage by CCl4, a chemical compound exerting a toxic effect on the liver. Ye et al. and Du et al consecutively reported protective effects of gypenosides on liver damage induced by CCl4 in rats. Zhu et al. reported effectiveness of 89% when using GP to treat 100 patients with hepatitis B. Ma et al. also treated 200 hepatitis B patients with gypenosides and saw a similar effect.
4, Preserve immunocompetence (Cancer Inhibition).
It is well known that both radio and chemo therapies suppress the immune system, and contribute to other degenerative changes in the body. A number of researchers have measured the effect of gypenosides on the immune system, malignant cell growth, white blood cell counts, and liver function especially in enhancing white blood cell, formation during radio and Chemotherapy and other conditions, which might cause leucopoenia. All the studies published to date have concluded that GP can help the body recover normal function after such treatment.
5, Provide extensive antioxidant protection for cells and biomembranes.
Oxidation of biological molecules and membranes by free radicals is closely related to a variety of disease states such as cancer, atherosclerosis, diabetes, liver disease, and arthritis. Researchers at Loma Linda University in California have shown that gypenosides from Gynostemma pentaphyllum are powerful antioxidants, capable of protecting biological systems during all stages of oxidant stress.
6, Act as a tonic for restoring the bodyù«s overall balance and enhancing physiological performance.
GP gypenosides have been shown to restore balance to blood pressure, blood lipid levels, reproductive function, and immunological response. In addition, GP gypenosides have powerful antioxidant effects, which help to preserve the bodyù«s many physiological systems.