Galanthamine Hydrobromide(Lycoris P.E.)

Professional manufacture supply natural /Galanthamine Hydrobromide(Lycoris P.E.)98%/Galanthamine Hydrobromide(Lycoris P.E.)99%

Short Description:

Hunan Huir Biological-tech Co.,Ltd is a proffessional manufacture produce Galanthamine Hydrobromide(Lycoris P.E.)98%/Galanthamine Hydrobromide(Lycoris P.E.)99% in china for more than 10 years.


Details Description:

Product Name:Galanthamine Hydrobromide

Original Plant:Shorttube Lycoris

Appearance:White to whitish crystal powder

Specification:99%

Synonym(s):Reminyl, Nivalin
Chemical Name:(4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide

Test Method:HPLC

Molecular Formula:C17H21NO3.HBr;C17H22BrNO3

Molecular Weight:368.27

CAS No.:1953-04-4


Pharmacology Action:Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type

Product introduction:
Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform,ether and alcohol.