CAS 459-30-0

Molecular weight:52.16
Molecular formula:C9H9FO
Package:10G/100G/25KG
Apparence:Yellow Liquid
Synonyms:(4-Fluorophenyl)acetone/ 1-(4-fluorophenyl)propan-2-one /4-Fluorophenylacetone

Description
This intermediate, also known as (4-Fluorophenyl)acetone, presents as a dark yellow liquid.
It is known to be insoluble in water. For best results, store in a tightly closed container in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
4-Fluorophenylacetone is incompatible with strong oxidizing agents. This chemical is a combustible liquid.

Chemical Properties
clear yellow liquid

Uses
4-Fluorophenylacetone is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
It is a haloarylacetone derivative used in a study of reversed enantiopreference of an ω-transaminase by a single-point mutation.

Application
(4-Fluorophenyl)acetone is a phenylacetic acid derivative that inhibits the 5-HT2 receptors.
It has been shown to have inhibitory activities against dopamine and serotonin by acting as an agonist at the receptor.
(4-Fluorophenyl)acetone also binds to nucleophilic sites on proteins, which may lead to inhibition of protein synthesis.
Brevibacterium sp. strain P7 was used as a model system and it has found that it inhibited the growth of this bacterium by binding to the enzyme RNA polymerase, preventing transcription and replication.