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For optimum benefit, the dosage should be individualized. Although most patients will be provided with the normal regular doses given below, some patients will require doses of more than 4 mg /
day. Dosage should be carefully optimized to prevent adverse effects in such situations. A dose of 0,25 to 0,5 mg should be given three times daily for treatment of patients with anxiety. The dose could be increased at intervals between 3 and 4 days to a maximum daily dose of 4 mg administered at divided doses to achieve the full therapeutical effect. The minimum appropriate dosage will be used and care needs regularly re-evaluated. Dose and length of therapy may increase the risk of dependence. Most people with panic issues have to use XANAX in doses higher than 4 mg daily to successfully treat the condition. Doses within the range of 1 to 10 mg daily have been used in controlled trials to mine XANAX 's effectiveness in panic disorder. The maximum daily dose was around 5-6 mg. Of the 1700 patients involved in PDD program, approximately 300 received XANAX in doses of more than 7 mg / day, including about 100 patients with maximal dosages of more than 9 mg / day. Some patients have been able to respond effectively by up to 10 mg per day.