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6-bromoandrostenedione
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Product Description
6-bromoandrostenedione
Chemical Name: 6-Bromo androstane-3,17-dione
CAS#:38632-00-7
Assay: 97%
A selective inhibitor of aromatase (estrogen synthetase) would be a useful pharmacological tool with potential therapeutic application. We have found that 6 alpha-bromoandrostenedione (6 alpha-BrA) is a competitive inhibitor of human placental aromatase with respect to androstenedione, with an apparent Ki of 3.4 nM, while 6 beta-BrA is a mechanism-based irreversible inhibitor with an apparent Ki of 0.8 microM and a kinact of 0.025 min-1. Aromatase activity was measured by tritium release into water from the 1 beta position of [1(-3)H,4(-14)C]androstenedione in reaction mixtures containing NADPH and the aromatase.
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SUPPLIER PROFILE
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| Company: | Wuhan YuanchengTech Development Co.,Ltd | ||
| City/State | Wuhan, Hubei | Country: |
China 
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| Business Type: | Export - Manufacturer / Trading Company | Established: | 1997 |
| Member Since: | 2007 | Contact Person | Steven-yu |
SUPPLIER PROFILE
City/State/Country -
Wuhan, Hubei
China
Business Type -
Export - Manufacturer / Trading Company
Established -
1997
Member Since -
2007
Contact Person -
Steven-yu