Follistatin Human Growth Muscle Building Peptides Follistatin 315 For Muscle Mass

Abstract

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.
The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA.

In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.


Application

Follistatin-344 Follistatin (also known as activin-binding protein) is an autocrine glycoprotein encoded by the FST gene that is expressed in nearly all tissues. Its primary function in the body is bioneutralization of members of the TGF-β superfamily, with a particular focus on activin and paracrine hormones. Follistatin is a potent Moystatin inhibitor. An original Follistatin acted also as an activin inhibitor, which on the other hand stimulates the secretion of follicle-stimulating hormone - FSH (activin regulates the growth and differentiation of all cell types, including cells within sexual glands, pituitary gland and skeletal muscles). Therefore, scientists developed a particular Follistatin (Follisttain-344) that is derived from the original one and that is capable of blocking preferentially Moystatin activity.