Flurbiprofen

Description

Flurbiprofen is a nonsteroidal anti-inflammatory drug effective in treating fever, pain, and inflammation in the body. It is similar to ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others. As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including injury, menstrual cramps, arthritis, and other musculoskeletal conditions. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation. Flurbiprofen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced.

Flurbiprofen is a member of the phenyl alkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. It is known as "Ansaid" marketed by "Froben" by Abbott.

Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges (Strepsils Intensive). A single enantiomer of flurbiprofen, tarenflurbil is currently in clinical trials for the treatment of metastatic prostate cancer.